Epilepsy MCQ Quiz

Explanation:

Drugs indicated for Absence Seizures

• ethosuximide – Drug of Choice
• valproic acid (VA)
• clonazepam
• methsuximide

Ref: Greenberg Textbook of Neurosurgery, 9th Edition, Chapter 26

Explanation:

Agents that interfere with platelet function and may increase the risk of bleeding complications:

• valproic acid
• phenytoin

Ref: Greenberg Textbook of Neurosurgery, 9th Edition, Chapter 26

Explanation:

Partial (simple or complex, with or without secondary generalization): the well controlled Veterans Administration Cooperative Study ranked the following drugs (based on seizure control and side effects) in this order :

1. carbamazepine (CBZ): most effective, least side effects
2. phenytoin (PHT): ↓
3. phenobarbital (PB): ↓
4. primidone (PRM): slightly less effective, more side effects

Ref: Greenberg Textbook of Neurosurgery, 9th Edition, Chapter 26

Explanation:

Agents that interfere with platelet function and may increase the risk of bleeding complications:

• valproic acid
• phenytoin

Ref: Greenberg Textbook of Neurosurgery, 9th Edition, Chapter 26

Explanation:

The following agents are considered “broad spectrum” (treat a variety of seizure types):

• valproic acid
• lamotrigine (Lamictal®)
• levetiracetam (Keppra®)

These agents are not considered broad spectrum:

• phenytoin (Dilantin®)
• carbamazepine (Tegretol®)

Ref: Greenberg Textbook of Neurosurgery, 9th Edition, Chapter 26